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Chunk #21 — Results — AVPR1A Expression Studies

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The AVPR1A gene and substance use disorders: association, replication, and functional evidence.
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The expression levels in samples from 26 individuals heterozygous and homozygous for the minor (T) allele of rs11174811 were higher than in 76 individuals homozygous for the major allele (unpaired t test with Welch's correction, two-tailed p = .01; Figure 3). After controlling for relevant covariates, the significance of the association increased (Table S2 in Supplement 1, p = .0003).