paperKB
coga / coga-kb
Help
Sign in

Chunk #30 — Results — Validation of the genetic factor scores

Source
Evidence for multiple genetic factors underlying the DSM-IV criteria for alcohol dependence.
Embedded
yes

Text

The pattern of results is of interest. The tolerance/excess drinking genetic factor most strongly predicted age at first drink and maximal drinks. The loss of control/social dysfunction genetic factor more strongly predicted conduct disorder symptoms, major depression, cannabis dependence, treatment seeking and fewer years of education. The withdrawal/continued use genetic factor was the only factor unrelated to years of education, and predicted conduct disorder symptoms nearly as strongly as factor 2. The results for number of episodes were of particular interest—as this was relatively strongly predicted by the loss of control/social dysfunction genetic factor but unrelated to the levels of the two other genetic factors.