To obtain a global picture of changes in gene expression in the hippocampi of alcoholics, we conducted a microarray study of post mortem hippocampi from 20 alcoholics and 19 controls. We report the differences in gene expression between alcoholics and controls and the pathways affected. We compare our results with genes identified in other human brain expression studies and in genome-wide association studies (GWAS) for alcohol dependence or phenotypes associated with alcohol use disorders to look for genes in common and the pathways they delineate.
