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Chunk #28 — Results — Correlations with clinical scores

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Subthalamic nucleus phase-amplitude coupling correlates with motor impairment in Parkinson's disease.
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Correlations between improvement in clinical scores and changes in mean power and PAC values between OFF and ON medication states were also estimated for the two beta ranges. This reflects whether individual clinical improvement was associated with within-patient changes in power/PAC. In general, similar trends can be observed as for the absolute values but effects were found to be weaker (Table 3, Table 4). Although correlation coefficients for PAC and spectral power in the low-beta range were almost as high as for the absolute values, their p-values no longer indicated a significant relation. This is possibly due to a loss of statistical power, given the large reduction in the number of samples.