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Chunk #15 — Results — Simulation study

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GPA: a statistical approach to prioritizing GWAS results by integrating pleiotropy and annotation.
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addition, we evaluated the actual FDR in the presence of linkage disequilibrium (LD) among SNPs. The details of the simulations and results are given in Figure S1 in Text S1. These results suggest that GPA can improve the power of identifying risk variants while controling FDR at the nominal level despite the mismatch between GPA and the generative model in our simulation study.