Prior genetic association studies (Gelernter et al., 1999; Lawford et al., 2006; Voisey et al., 2009; Bailey et al., 2010) of PTSD have included DRD2 SNPs, but failed to examine risk associated with either rs12364283 or SNPs with which it is in high LD. These investigations (Gelernter et al., 1999; Lawford et al., 2006; Voisey et al., 2009; Bailey et al., 2010) include both positive and negative reports; however, evidence of association based on this literature is not compelling. It is important to note that prior studies also differed from the current report in that none had a sample with a high prevalence of amphetamine dependent individuals.
