Most suicide research and prevention efforts have focused on youths and older adults. Although the analysis in this report does not explain why suicide rates are increasing so substantially among middle-aged adults, the results underscore the importance of prevention strategies that address the needs of persons aged 35–64 years, which includes the baby boomer cohort. Prevention efforts are particularly important for this cohort because of its size, history of elevated suicide rates, and movement toward older adulthood, the period of life that has traditionally been associated with the highest suicide rates (3,8).