Chunk #10 — Role of nSMase1 in Lipid Metabolism and in Cellular Signaling

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Mammalian neutral sphingomyelinases: regulation and roles in cell signaling responses.

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Taken together, these data suggest that nSMase1 may function as an in vivo SMase in some instances. However, with the lack of a phenotype in the nSMase1-KO mouse, the physiologic roles of nSMase1 still need to be further determined.