We recently completed genome-wide genotyping in COPDGene, a large, genetic epidemiology study of over 10,000 non-Hispanic White and African American cigarette smokers (both current and ex-smokers) with and without COPD21. We sought to determine whether a genome-wide association study (GWAS), combining the results from COPDGene with previous association studies7, would reveal new genetic susceptibility loci.
