broad pattern observed was the high correlation among brain tissues (median Spearman’s ρ of 0.584 (cis) and 0.241 (trans)) and among non-brain tissues (median Spearman’s ρ of 0.606 (cis) and 0.165 (trans)), with much lower correlation observed between these two groups (median Spearman’s ρ of 0.499 (cis) and 0.096 (trans)). Within non-brain tissues, we observed strong correlation among closely related tissues, such as arterial tissues (median Spearman’s ρ of 0.743 (cis) and 0.264 (trans)), skeletal muscle and heart tissues (median Spearman’s ρ of 0.672 (cis) and 0.184 (trans)), and skin tissues (Spearman’s ρ of 0.804 (cis) and 0.365 (trans)). Overall, the median pairwise correlation between tissues was 0.547 (cis) and 0.138 (trans).
