Studies with rodents elucidated some genetic factors for the association between sweet taste and alcohol. In mice and rats, positive correlations between preferences for ethanol and sweeteners were found among various strains and in segregating crosses.[105,112,123,124,149,150,181-189] Genetic analysis of a cross between mice from a high ethanol- and sweetener-preferring C57BL/6ByJ strain and a low ethanol- and sweetener-preferring 129P3/J strain suggested that the strain differences in sweetener and ethanol consumption depend on relatively small and partially overlapping sets of genes.[124]
