The UoB program currently has 640 community participants, of which 31% have been enrolled since its commencement in 2002. The majority of donors are female (60%) with an age range of 23–95 years; males are aged 27–101 years (Fig. 2). Longitudinal data about medical history, lifestyle, and cognition are collated, which enhances the characterization of the cases. Since 2003, 1100 cognitive assessments and 104 MRI scans have been performed. Of the successful donations (120), 55 donors have had cognitive assessments, of which 11 have also had an MRI. More than half of the current participants have expressed an interest in engaging in research opportunities offered.
