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Chunk #42 — Discussion

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A computational tool (H-MAGMA) for improved prediction of brain-disorder risk genes by incorporating brain chromatin interaction profiles.
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Finally, we found intricate relationships among genes impacted by common and rare variation. For example, common and rare variation in SCZ and ASD coalesce to the same set of genes, highlighting the importance of studying risk variation across the allele frequency spectrum to comprehensively understand the complex interplay between common and rare variation in psychiatric disorders.