Over the past 10 years, developments in non-invasive neuroimaging, most notably in functional magnetic resonance imaging (fMRI), have increased our ability to safely study the developing brain and to harmonize data across multiple platforms. Large-scale projects such as the Human Connectome Project (HCP), designed to map the neural pathways that underlie human brain function, have established standards for conducting large-scale neuroimaging projects. The HCP developed a set of broadly useful, thoroughly tested, MRI acquisition protocols, image reconstruction algorithms, and numerous publicly available neuroimaging software and informatics tools that have informed ABCD’s neuroimaging protocol development (Van Essen et al., 2012).