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Chunk #4 — Subjects and Methods — Study samples

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Linkage analysis followed by association show NRG1 associated with cannabis dependence in African Americans.
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The basic demographic information for the three samples involved in each stage of the study is summarized in Table 1. The following section provides details of the sample recruitment and characteristics for each sample set. Written informed consent was obtained from all subjects; the IRB at each recruitment site approved the study, and NIAAA and NIDA issued certificates of confidentiality for the work.