populations are from Wang et al.[23]. The approximate location of the Mestizo and Native American populations included in the analyses is shown in Figure 1. Additional geographic and demographic information for the urban areas sampled is shown in Table S1. Sampling sites mostly correspond to one location. When more than one location was sampled in a given region, the census information provided is the sum of these locations and the sample was given a regional denomination (e.g. the Rio Grande do Sul (RGS) sample was collected in the cities of Bagé and Alegrete, in the Brazilian state of RGS).