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Chunk #28 — Results — Acute ethanol application causes an increase in the overall inhibitory tone in MOR N40 AD-iNs

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Differential sensitivity of human neurons carrying μ opioid receptor (MOR) N40D variants in response to ethanol.
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MOR N40 and D40 AD-iNs, and this difference was not detected following ethanol application. These data suggest that acute ethanol application results in an enhancement in network and/or synaptic activity in a relatively homogenous population of inhibitory N40 AD-iNs, suggesting an increase in the overall inhibitory tone.