As detailed elsewhere (Hancock et al., in press, Johnson et al., 2015), stored serum samples from the UHS were restored using the Illumina Formalin-Fixed Paraffin-Embedded kit to maximize the quality of genomic DNA and then genotyped on the Illumina Omni1-Quad BeadChip, Controls were genotyped on one of three Illumina platforms (Omni1-Quad, 1M-Duo, or Omni2.5). Both ZNF804A SNPs, rs7597593 located in intron 1 and rs1344706 located in intron 2, were assayed across these Illumina platforms and thus genotyped in all cases and controls. Both ZNF804A SNPs passed all quality control thresholds, thus having call rate ≥90%, minor allele frequency ≥1%, and Hardy Weinberg equilibrium P≥1×10−4.
