The risk for relapse and adverse outcomes is especially a concern for individuals who misuse alcohol, a substance which is readily available and is the most common substance of abuse in the United States after nicotine [13]. For example, in the National Comorbidity Survey-Replication, about 13% of the US adult population were estimated to have a lifetime history of alcohol abuse and over 5% were estimated to have a lifetime history of alcohol dependence [14].
