on chromosome 3 with MaxDrinks in the combined SAGE and COGA samples (p=4.3 x 10-8). It is noteworthy that the p value in that study did not reach the conventional value of 5x10-8. We did not replicate either finding. The SAGE sample is composed of both EA and AA populations and their study did not address population stratification, which makes it difficult to interpret these findings. As discussed above, risk loci for MaxDrinks may differ across populations. Thus, population admixture may contribute to inconsistent findings.
