We investigated the unreported novel SNVs and their proxies (r2 ≥ 0.8) across 44 tissues available in the GTEx dataset (20) for eQTLs. We reviewed the results for SNV-eQTL associations across all tissues, focusing on the heart, nerve, lung, muscle, adrenal and brain tissues which may be relevant tissues for HR based on known physiology of HR and our results from the enrichment analysis. Genes reported as eQTLs are based on study-specific significance thresholds (P-values < 10−8) and r2 ≥ 0.8 between HR-SNV and top-eQTL SNV (the SNV most significantly associated with transcript).
