Chunk #38 — Discussion

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Integration of summary data from GWAS and eQTL studies identified novel causal BMD genes with functional predictions.

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In conclusion, the present study identified that ASB16-AS1 and SYN2 may causally affect BMD through their gene expression. ASB16-AS1 may play an important role in osteoblast proliferation and differentiation, at least by interacting with known genes in these processes.