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Chunk #11 — Results — Asymmetry Analyses involving DFA and Rest Data: Test of the Capability Model — Lifetime MDD status

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Resting and task-elicited prefrontal EEG alpha asymmetry in depression: support for the capability model.
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Although resting frontal EEG alpha asymmetry data from the present sample were reported in Stewart, Bismark, et al. (2010) and state frontal EEG asymmetry data were reported in Stewart et al. (2011), they are included here to test the capability model hypothesis that state EEG manipulations produce larger differences between depressed and non-depressed individuals than resting EEG. To examine the relationship between lifetime MDD status and frontal EEG asymmetry, full factorial mixed linear models (SAS 9.2) were run for each reference mode (AVG, CSD, Cz, and LM) separately with lifetime MDD status (past and/or current MDD = lifetime MDD+, never depressed = lifetime MDD−) and biological sex (male, female) as between-subjects variables and condition (approach faces, withdrawal faces, rest) and channel (F2-F1, F4-F3, F6-F5, F8-F7) as within-subjects variables. EEG asymmetry score based on total (8–13 Hz) alpha power was the dependent variable. An approach facial-expression DFA asymmetry score was computed by averaging across asymmetry during angry and happy faces for the four days of EEG recording, whereas a withdrawal facial-expression DFA score was calculated by averaging across asymmetry scores during