Effect sizes and p values for CpG sites were used from the EWAS results as presented in the original publication [15]. In brief, the EWAS model was based on methylation M-values as the dependent variable and AUD status as the predictor. As covariates, sex, age, postmortem interval (PMI), pH-value, estimated smoking, standardized neuronal cell count, and the first ten principal components of the EPIC array internal control probes were included.
