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Chunk #25 — RESULTS — Coexpression in the adult subventricular neurogenic niche

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Functional organization of the transcriptome in human brain.
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it has been shown that SVZ astrocytes divide in vivo and are capable of generating neurons in the absence of exogenous growth factors in vitro45. Although it is unclear whether gene coexpression in M13C primarily reflects transcription in a single cell type or in multiple cell types, the strong membership of so many astrocytic genes (Supplementary Tables 5 and 7) suggests that SVZ astrocytes contribute substantially to the observed coexpression patterns in this module. These observations are consistent with the interpretation that gene coexpression in M13C may relate to the maintenance of adult neural progenitors and the process of neurogenesis.