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Chunk #35 — Results — Further Examination of the Relationship between TF-PCA and Time-Domain Measures — Mean ERP amplitude within the time range defined by TF-PC3

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Relationship between the P3 event-related potential, its associated time-frequency components, and externalizing psychopathology.
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We additionally sought to demonstrate that the information contained in the TF-PCA components is the same as that contained in the condition average ERP time-domain measures – but characterized in a more optimal way. To this end, we extracted a new time-domain measure based on the TF-PCA optimized time window spanned by PC3 (given PC3’s unique association across externalizing groups). Probit regression analyses were performed for each diagnostic group comparing the activity in the time and TF domains residing within a time window defined by the time range spanned by PC3. As seen in Figure 1, the activity in PC3 lasts from 140–500 ms, spanning an interval containing the P2-N2-P3 ERP complex in the time domain and TF-PCA components 1, 3, and 5 in the TF domain. In the first set of analyses, the ability of the mean time-domain ERP amplitude within this time range to differentiate each diagnostic group from controls was compared to the ability of a model containing the peak energies, collectively, of the TF-PCA components that occurred within this same time range to do so (i.e.