The subjects were sampled from a larger data set generated by the multi-site Collaborative Study on the Genetics of Alcoholism [COGA (44)]. They resided within 150 miles of one of COGA’s six participating sites (Indiana University School of Medicine; SUNY Health Science Center, Brooklyn; University of California at San Diego; University of Connecticut Health Center; University of Iowa Health Center; and Washington University School of Medicine). All provided written, informed consent prior to participation. They were financially compensated for their time and effort.