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Chunk #46 — Conclusion

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The Detection of Phase Amplitude Coupling during Sensory Processing.
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In conclusion, we have outlined the key analysis steps for detecting changes in alpha-gamma PAC during sensory processing, using an example visual MEG dataset. While alpha-gamma PAC was shown to increase, the specific patterns of alpha-gamma coupling depended upon the specific algorithm employed. Follow-up analyses showed that these results were not driven by non-sinusoidal oscillations or insufficient data. In future, we hope that a variety of PAC algorithms will be implemented alongside existing open-source MEG toolboxes (Oostenveld et al., 2010; Tadel et al., 2011; Gramfort et al., 2014), with detailed guidance and advice, so that PAC can form a natural analysis step in electrophysiological research.