Table 1 summarizes the COGA-AA and COGA-EA subsamples. Compared to those in COGA-AA, individuals in COGA-EA had higher mean DSM-IV AD criterion count in both AD cases and controls, SRE-T, and SRE-5 scores. Latent genetic influences (familial h2) contributed to 21-31% of the variance in SRE scores, indicating moderate heritability (Table 2). Overall, genetic correlations (rg) with AD and DSM-IV AD criterion count were higher for SRE-T (rg=0.49 -0.76) than for SRE-5 (rg=0.35-0.48) (Table 2).
