The findings of each section lend their own contribution to further understand the neurobiology underlying the ADHD symptomatology and each can stand alone, so we consider them one by one, but we also conclude by considering them together. As an overview, in the first section we found that NAcc is atypically connected to several cortical regions in children with ADHD, including regions previously shown to present atypical correlated spontaneous activity in adults and children with the disorder (Castellanos et al., 2008; Fair et al., 2010; Mills et al., 2012). This is a new finding important in its own right. Then, in sections two and three, we showed that many cortico-NAcc connections play a role in reward valuation, consistent with other studies on the role of this circuit. However, the impairment of only specific connections may be related to pathophysiology of specific behavioral dysfunctions in ADHD. All these findings are consistent with atypical functioning of the NAcc and suggest that it may be linked to a specific behavioral domain (impulsive decision making) as a component phenotype of ADHD.
