Studies of teens (119;120) and adults (121) indicate that persistent tobacco use is associated with a poorer response to treatment for cannabis use disorders. For example, among teens, persistent non-tobacco smokers and those who quit tobacco use relapsed to cannabis less rapidly and showed reduced odds of relapse to cannabis compared with persistent smokers or those who initiated smoking [104]. Among adults, current tobacco smokers reported more psychosocial problems and achieved poorer cannabis abstinence outcomes than ex-smokers (121).
