Finally, intranetwork and internetwork connectivity were examined via the MANCOVAN toolbox34 available in GIFT.28 Temporal synchrony between component networks (ie, internetwork connectivity) was examined via functional network connectivity (FNC) correlations.34 FNC correlations allow inferences regarding coordinated activity between networks of interest (indexed by internetwork temporal synchrony) and potential associations among these indices and group, the number of first- and second-degree family members with an AUD, age, sex, and parental education level. In computing FNC correlations, network timecourses were detrended (filter cutoff = 0.15 Hz) but were not despiked to avoid redundancy with the initial preprocessing stage. Subsequently, correlations were computed between timecourses between components.
