wide linkage disequilibrium, and we highlight 12 loci that feature meQTL p-values < 1.0×10−20 in Figure 4. These CpGs associated with risk variants map to TOM1L2, ITIH1, MAD1L1, NT5C2, OGFOD2, MMP16, BCL11B, PLCH2, SLC12A4, CACNA1C, WBP2NL, and C2orf82. DNAm levels proximal to risk variants for schizophrenia may therefore influence or possibly mediate the effect of genotype on clinical risk for a large proportion of genome-wide significant loci.
