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Chunk #14 — Results — Spring-embedded visualization in combination with functional connectivity suggests that regions are linked more locally in childhood and are more distributed in adulthood

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Functional brain networks develop from a "local to distributed" organization.
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One of the primary observations from the movie relates to this anatomical-functional distinction. In children, regions appear to be largely arranged by anatomical proximity. This arrangement can be seen in Figure 2 and Video S1 where, in children, regions can be readily grouped by cerebral lobe (outline colors of spheres in Figure 2 and Video S1). Over age, as functional connections mature, the node arrangements change such that anatomically close regions are now largely distributed across the graph layout, in a pattern more aligned with the mature networks' functional properties (core colors of spheres in Figure 2) [21], [36]–[39]. Thus, across development, local clusters of regions “segregate” from one another and “integrate” into more distributed adult functional relationships with more distant regions.