More broadly, these new studies could have important clinical implications. Atypical social decision-making is commonly reported in several disorders including conduct disorder, psychopathy, autism and frontotemporal dementia (Anderson and Kiehl, 2012; Henry et al., 2016; Lockwood, 2016). Yet, very seldom have computational models been used to understand the neuroanatomical areas that are implicated. There is initial evidence that social prediction error signalling may be disrupted in those with autism spectrum disorder (Balsters et al., 2016a) and in social anxiety disorder (Koban et al., 2017). In addition, some studies have suggested different contributions of sgACC and pgACC to mood disorders such as depression (Drevets et al., 1997; Mayberg, 1997). The recent work reviewed here points to the utility of using computational models along with self and caregiver report to provide new avenues to understand the neuroanatomy implicated in these disorders.
