In the larger study, families with at least one alcoholic parent (from the first-generation) were recruited using court DUI records, health maintenance organization wellness questionnaires, and community telephone surveys. Telephone surveys were used to recruit families without parental alcoholism, who were matched to families with parental alcoholism on demographic characteristics. See Chassin et al. [46] for details. For the current analyses, at T1, participants (from the third-generation) and their parents (from the second-generation) were interviewed at home. Out-of-state participants were interviewed via telephone or mailed surveys. Buccal and saliva samples using Oragene kits were used to collect biological samples containing DNA. At T2, participants were interviewed via telephone or mailed questionnaires. Participants and parents provided written informed consent and/or assent at all assessments.
