The cerebral cortex processes motor, sensory, and associative information and is expanded in primates, especially humans (Buckner and Krienen, 2013). Little is known about what molecular specializations contribute to region-specific cortical function. We first determined how accurately our cortex datasets reflect the true balance of cellular populations in vivo and then identified transcriptional specializations within each non-neuronal cell class and across glutamatergic and GABAergic neurons.
