The most important task of the phenotype-specific WGs is to determine the feasibility and logistics for cross-study analyses related to a given phenotype. The WGs' reviews need to take into account each study's data scope, consent limitations, and study design, including the actual questions asked, data collection protocols, phenotype definitions, possible values or responses, estimated number of individuals for whom there would be phenotype data, and any other factors that might influence analyses. The primary considerations fall into seven main categories:
