Chunk #18 — Materials and Methods — Real datasets — Haplotype accuracy in explicitly related individuals

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A general approach for haplotype phasing across the full spectrum of relatedness.

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next most competitive method) taking the implied duo and trio information into account. We refer to this as the Beagle duo/trio method. Beagle was found to use substantially more memory in this setting (over 150 GB for the GPC cohort) which may be problematic for some researchers. This issue is noted in the Beagle manual and relates to missing data in parent-offspring duos and trios.