The prevalence (presence/absence) and severity scores for childhood trauma in both AD and CON subjects are presented in Table 2. Childhood trauma exposure was significantly more prevalent in the AD subjects, with odds ratios ranging from 3.5 (95% CI 2.1–5.9) for physical abuse to 11.5 (95% CI 5.8–22.8) for emotional abuse. Severity scores were also significantly higher in the AD subjects, with effect sizes ranging from medium to large (Cohen’s d of 0.6 to 1.0). Of the five individual types of trauma, emotional abuse and neglect were the most frequent among the AD subjects. In addition, a much higher number of AD subjects experienced more than one type of childhood trauma, compared to CON subjects.
