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Chunk #18 — Methods — Study population — Healthy controls

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A stable pattern of EEG spectral coherence distinguishes children with autism from neuro-typical controls - a large case control study.
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Exclusion criteria were as follows: (1) diagnosed neurologic or psychiatric illness or disorder or expressed suspicion of such, for example, global developmental delay (GDD), developmental dysphasia, attention deficit disorder (ADD) and attention deficit with hyperactivity disorder (ADHD); (2) abnormal neurological examination as identified during the research study; (3) clinical seizure disorder or EEG reading suggesting an active seizure disorder or epileptic encephalopathy (Note: Subjects with rare EEG spikes were not excluded); (4) noted by the research psychologist or neurologist to present with autistic features; (5) newborn period diagnosis of intraventricular hemorrhage (IVH), retinopathy of prematurity, hydrocephalus, or cerebral palsy or other significant condition likely influencing EEG data; and/or (6) taking medication(s) at time of EEG study. A total of 571 patients met the criteria for neuro-typical controls and were designated as the study's control (C) sample.