paperKB
coga / coga-kb
Help
Sign in

Chunk #44 — 3. Results — 3.2. Electrophysiologic data — 3.2.3. Randomization tests of topographic old/new effects

Source
Current source density (CSD) old/new effects during recognition memory for words and faces in schizophrenia and in healthy adults.
Embedded
yes

Text

For the total sample (N = 101), both factors 442 and 723 yielded highly significant overall topographic old/new effects for each task (all multivariate T2 ≥ 7.74, all p ≤ 0.005; Figure 6AB). For the P3 source (factor 442), mid-frontal old/new effects were prominent in both tasks, as evidenced by univariate max(T2) statistics at each site (Figure 6A, column 4). However, these early old/new effects were somewhat more robust and broader for words (at FPz, AFz, Fz, FCz, Cz, F1, F2, FC1, FC2, AF4, all T2 > 30.9, all p < 0.0001) than faces (at AFz, Fz, FCz, Cz, F2, FC2, all T2 > 39.4, all p < 0.0001). These mid-frontal old/new effects were accompanied by inverted old/new effects (i.e., more negative-going sources for old than new items) at lateral anterior-frontal sites, particularly for words. There were also mid-occipitoparietal old/new effects for words (at POz, Oz, all T2 > 39.3, all p < 0.0001; at Pz, T2 = 14.6, p = 0.03) and faces (at POz, T2 = 14.2, p = 0.02; at Pz, T2 = 12.8, p = 0.04), which were accompanied by inverted old/new effects at lateral inferior temporoparietal sites, primarily for words and over the left hemisphere.