by macrophages that likely inhibits the release of cytokines by inhibiting translation of TNF-α mRNA [59]. Adipogenesis, which is the process in which preadipocytes differentiate into adipocytes, may also involve Cd14. Acute inflammation of adipose tissue is important in tissue protection, remodeling, and expansion [60], and Cd14 modulates adipose tissue inflammatory activity [61]. Most of the evidence suggest that the cytokine signaling pathway and proinflammatory cascade represent a significant intersection for these pathways.
