Chunk #12 — Materials and methods — Expression QTL analyses

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Integration of GWAS SNPs and tissue specific expression profiling reveal discrete eQTLs for human traits in blood and brain.

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Starting with 447 subjects in the brain series, after data normalization and quality control, the brain mRNA dataset included 399 samples and ~ 9000 mRNA probes that were detected in > 95% of all samples. The blood dataset started with 712 samples, of which 501 passed all our QC steps; 5094 mRNA probes were detected in > 95% of samples.