To fill this gap, we did a systematic review and network meta-analysis of double-blind randomised controlled trials in children, adolescents, and adults with ADHD, using data from published reports and unpublished data gathered systematically from drug manufacturers or study authors. We aimed specifically to compare ADHD medications in terms of efficacy on core ADHD symptoms, clinical global functioning, tolerability, acceptability, and other clinically important outcomes—eg, blood pressure and weight changes.
