Chunk #19 — Methods and results — A reparameterization of the equation to address the problem

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Testing for measured gene-environment interaction: problems with the use of cross-product terms and a regression model reparameterization solution.

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In the second half of this paper we focus on constructing a model that appropriately captures gene-environment interactions with a three level genotype, i.e., one that accurately produces Eqs. (A1)–(A3) in Appendix A.