the maximum NLOD score in the 10p15 region was decreased to 1.79. These investigators followed up the linkage findings with a family-based association analysis which examined 35 single-nucleotide polymorphisms (SNPs) in this 10p15 region. Association was detected on 10p15 with three adjacent SNPs, including the amino acid variant rs2271275 in the 3' region of adenosine deaminase acting on RNA 3 (ADAR3) (P<.05).
