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Chunk #21 — GABRG1 haplotype associations — Finnish Caucasians — Long-distance haplotypes across GABRG1 – GABRA2: influence of GABRG1 on association with AUD

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GABRG1 and GABRA2 as independent predictors for alcoholism in two populations.
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Figure 4 shows that in the Finnish Caucasians and Plains American Indians there is a degree of LD extending from GABRA2 block 2 to downstream of GABRG1. For example, D′ between rs1504501 (in the intergenic region distal to GABRG1) and GABRA2 block 2 SNPs was 0.6 in the Finns and 0.4 in the Plains Indians.