Chunk #22 — Results — eQTL Replication

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Mapping of gene expression reveals CYP27A1 as a susceptibility gene for sporadic ALS.

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The eQTL replication set comprised 161 ALS patients and 206 control samples (Table S1). 951 out of 1,108 selected SNP-transcript pairs in cis were significantly replicated (Figure 1). The eQTL SNPs of these SNP-transcript pairs were selected for replication in the GWAS replication data.