The current study evaluated the inter-rater reliability and diagnostic concordance of Thai versions of the SSADDA and MINI developed for genetic studies of OD in Northern Thailand. In brief, the study confirmed anecdotal reports of historically high levels of lifetime OD among villagers and demonstrated excellent inter-rater reliability for Thai versions of both the MINI (K=1.00) and the SSADDA (K=0.97) as assessed by Cohen’s κ (Cohen, 1988). We also found excellent agreement between instruments (κ =0.97), consistent with the concurrent validity of the diagnosis and the utility of either instrument to assess the phenotype of OD in our Hmong study population.